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A 46-year-old Woman with A History of Multiple Sclerosis Presenting with Abdominal Pain: A Case Report and Discussion
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Nazanin Nourbakhsh   |
| Hematology, Oncology & Bone Marrow Transplant Research Center |
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Abstract: (25 Views) |
A 46-year-old woman with a history of multiple sclerosis and aortofemoral bypass surgery presented with sudden pain in the left side of the abdomen. Physical examination revealed tenderness in the left hypochondrium, and abdominal imaging confirmed splenic infarction. Further investigations detected the presence of antiphospholipid antibodies in her blood, supporting the diagnosis of antiphospholipid syndrome (APS) as the likely underlying cause. APS is an autoimmune disorder that leads to abnormal thrombosis formation in vessels and can manifest as either arterial or venous thrombosis, recurrent miscarriages, and organ involvement, including the kidneys, brain, and heart.
APS is more commonly seen in younger individuals and women, either as a primary condition or secondary to lupus. The cornerstone of treatment involves anticoagulation therapy, typically with heparin and warfarin, to prevent further thrombotic events. In acute cases, more aggressive interventions such as plasmapheresis or corticosteroids may be necessary. The patient was treated with anticoagulants, and after stabilization, she was discharged with recommendations to prevent future complications. |
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| Keywords: Abdominal pain, Anticoagulation, Antiphospholipid syndrome, Autoimmune disease, Thrombosis |
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Full-Text [PDF 488 kb]
(11 Downloads)
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Type of Study: Applicable |
Subject:
General
Received: 2025/08/9 | Accepted: 2025/01/29 | Published: 2025/01/29
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